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Maurocalcine
簡(jiǎn)要描述：Smartox Biotechnology是*一家專(zhuān)門(mén)生產(chǎn)動(dòng)物毒液多肽毒素，用于細(xì)胞離子通道功能研究的生物醫(yī)藥公司。多肽毒素在生物制藥領(lǐng)域具有重要的使用價(jià)值。
產(chǎn)品型號(hào)：07MAU001- 廠(chǎng)商性質(zhì)：代理商
- 更新時(shí)間：2024-10-29
- 訪(fǎng) 問(wèn) 量：1483
產(chǎn)品介紹
Maurocalcine
Agonist of ryanodine receptors(魚(yú)尼丁受體激動(dòng)劑)
Maurocalcine, a component of the venom of Scorpio maurus palmatus, was discovered by Michel De Waard, co-founder of Smartox. folds according to an inhibitor cysteine knot. Such as Imperatoxin A, acts as a high affinity agonist of the type-1 ryanodine receptorexpressed in skeletal muscles with an affinity in the 10 nM range. induces an increase in channel opening probability accompanied by sudden transitions to long lasting subconductance states. has also been characterized as a cell penetrating peptide and its pharmacological activity can be observed upon extracellular perfusion.
技術(shù)資料
氨基酸序列：
Gly-Asp-Cys3-Leu-Pro-His-Leu-Lys-Leu-Cys10-Lys-Glu-Asn-Lys-Asp-Cys16-Cys17-Ser-Lys-Lys-Cys21-Lys-Arg-Arg-Gly-Thr-Asn-Ile-Glu-Lys-Arg-Cys32-Arg-OH
二硫鍵： Cys3-Cys17, Cys10-Cys21 and Cys16-Cys32
長(zhǎng)度 (aa)：33
分子式： C156H260N56O46S 6
分子量： 3858.8 Da
外觀(guān)： White lyophilized solid
可溶性： water and saline buffer
CAS 號(hào)：not available
來(lái)源：Synthetic
純度： > 98 %
產(chǎn)品信息
07MAU001-00100 | 0.1mg | |
07MAU001-00500 | 0.5mg | |
07MAU001-01000 | 1mg |
