2015年第54期毒理學協(xié)會年度會議(Society of Toxicology Annual Meeting and ToxExpo,SOT)，于2015.03.22—2015.03.26在圣地亞哥（San Diego, CA, USA）舉辦

22.03.-26.03.2015 - SOT 2015 - San Diego, CA, USA

insphero的展位號是2283（Meet InSphero at Booth #2318）

insphero參與SOT會議，讓3D（三維）細胞毒性檢測變得更簡單（Discover 3D Toxicity Testing Made Simple）

下載insphero指南（Download your InSphero guide to SOT 2015）鏈接地址：http://www.qbioscience。。ｃｏｍ/FileUPLoad/DownLoadFile/635628055064687500.pdf

insphero的3D細胞培養(yǎng)系列產(chǎn)品鏈接地址：http://www.qbioscience。。ｃｏｍ/Brand_T24.html

在2015年第54期毒理學協(xié)會年度會議(Society of Toxicology Annual Meeting ,SOT)上，有8個海報展示，三個參展商，和我們inspherozui大的ToxExpo展位以及Beers and Spheres 聯(lián)誼會。今年的SOT會議insphero會提供更多的機會，讓您更好的學習用3D微組織模型來預測毒性和進行安全性測試，主要包括以下內(nèi)容：

1.生物行業(yè)的*如Genentech, AstraZeneca, Biognosys,和PerkinElmer， 正在尋找3D肝臟微組織（3D InSight^TM Liver Microtissues）作為*的模型來評估長期毒性（long-term toxicity）、ADC介導的毒性（ADC-mediated toxicity），藥物性肝損傷陽性率（DILI predictivity），化合物治療蛋白質(zhì)組學剖析（compound-treated proteomic profiling），transporter efflux activity ，以及。。。

2.除了通過3D肝臟模型研究毒性外，還可以構(gòu)建胰島、心臟和神經(jīng)3D模型來研究藥物毒性

3.學習并與生物行業(yè)的細胞水平藥物篩選，蛋白質(zhì)組學，成像公司合作，確保您能充分利用3D模型系統(tǒng)

4.與insphero的3D專家討論如何定制合同研究項目，已滿足您的實驗需求

5.參與我們的Beers and spheres聯(lián)誼會——3月23日，星期一，下午7點

鏈接地址：http://www.insphero。。ｃｏｍ/company/fairs-conferences-and-events/sot-2015#exhibitor

海報展示Poster Presentations

Defeating the Animal: Alternative Systems for Neurotoxicity Testing
(presented by IfADo, Dortmund, Germany)
Abstract #248, Poster Board #414
Monday, March 23: 9:30 AM - 12:30 PM

Prodrug Activation in a Dynamic Microfluidics System Interconnecting Liver and Tumor Microtissues 
Abstract #449, Poster Board #136
Monday, March 23:  1:00 PM - 4:30 PM  

Standardized Rat and Human Microislets for Diabetes Research and Drug Safety Assessment
Abstract #1201, Poster Board #632
Tuesday, March 24: 9:00 AM - 12:30 PM

Evaluation of Spherical Liver Microtissues for In Vitro Cytotoxicity Assessment of Antibody-Drug Conjugates
(Presented by Genentech)
Abstract #892, Poster Board #115
Tuesday, March 24: 9:00 AM - 12:30 PM

Quantification of Efflux Transporter Activity in 3D Human Liver Microtissues
(Collaboration with PerkinElmer)
Abstract #2635, Poster Board #340
Thursday, March 26: 8:30 AM - 12:00 PM

Global Proteomic Profiling of Acetaminophen-Exposed 3D Human Liver Microtissues Identifies Novel NAPQI Adduct Sites
(Collaboration with Biognosys AG)
Abstract #2589, Poster Board #251
Thursday, March 26: 8:30 AM - 12:00 PM

Evaluation of the 3D InSight^TM Human Liver Microtissues for the Detection of Compounds That Cause Drug-Induced Liver Injury in Humans
(Presented by AstraZeneca)
Abstract #2569, Poster Board #231
Thursday, March 26: 8:30 AM - 12:00 PM

Transmembrane Potential Measurements in Cardiac Microtissues Derived from Human Stem Cells
(Presented by University of Glasgow)
Abstract #2840, Poster Board #659
Thursday, March 26: 8:30 AM - 12:00 PM

Modifications Required for ATP and Caspase Detection Assays Applied to 3D Cell Spheroids
(Presented by Promega Corp.)
Abstract #2577, Poster Board #239
Thursday, March 26: 8:30 AM - 12:00 PM

Exhibitor Hosted Sessions參展商舉辦會議

Join us for free continental breakfast!

3D microtissue cultures: use in long-term hepatocyte ADME-Tox studies Co-presented with BioreclamationIVT
Monday, March 23
9:15 AM - 10:15 AM
Room 24B

InSphero and BioreclamationIVT present the latest data on the characterization of 3D human liver microtissues and their application to toxicity testing, drug metabolism studies and disease modelling. In addition, the attendees will learn about donor-to-donor differences and the use of liver non-parenchymal cells for 3D liver cultures.

3D microtissues meet OMICS technologies and high-content imaging
Monday, March 23
3:15 PM - 4:15 PM
Room 24C

OMICS technologies and high-content imaging have been demonstrated to be valuable tools to unravel biological pathways and phenotypic outcomes. This session aims to introduce the use of confocal imaging techniques, transcriptomics and proteomics in combination with organotypic 3D model systems to assess toxicological pathways and mechanisms.

3D liver models and beyond: 3D hepatic, cardiac, pancreatic, and neural microtissue models for toxicity testing
Tuesday, March 24
2:30 PM - 3:30 PM
Room 24C

3D liver microtissue models have demonstrated significant value as more organotypic systems for assessment of toxicity.  This session aims to cover the latest studies characterizing 3D InSight? liver microtissues, and introduce novel 3D models for assessment of toxicity in non-liver organs, focusing on the heart, pancreas, and brain.   

Join us for cocktails at our 'Beers and Spheres' Event

Co-hosted by Promega and Cellular Dynamics International

Monday, March 23 7:00 PM - 10:00 PM
Don Chido - San Diego Gaslamp
527 5th Avenue
San Diego, CA 92101